Bone cancer is divided into two, namely primary and secondary bone cancer. Primary bone cancer if the cancer appeared and developed directly into the bone. During the secondary bone cancer, a cancer that covers its origins in other parts of the body is to the bone.
The whole bone in the body might be are affected by the disease, but occur mostly in the bones of the lower leg and arm.
The three most important are signs and symptoms of cancer bone disease, namely:
• Pain. Pain in the area of bone of that was attacked, feel concerned someone of bone cancer and the pain increases during the move. Pain is usually to night constantly felt.
• Swelling. The area around the affected bone cancer experience swelling and redness. If the swelling in the bone near the joints, a motion would be difficult and limited.
• brittle bones. Bone causing bone cancer are weak and brittle. Even if it’s hard, could be mild or minor injuries fall alone bone break.
In addition, there are also some other symptoms, such as a feeling of pigeons fingers and numbness, pressing the cancer in the spine innervation, reflected the lump on the bone, the body feels tired, weight loss, fever above 38 ° C, temperature and sweating especially at night.
Adult bone pain symptoms is sometimes wrong than arthritis. It is sometimes misinterpreted as a side effect of the bone growth in children and adolescents. It is recommended to see a doctor if you or your child constantly feeling the pain in the bones or pain continues to worsen.
The bone is formed from various components: osteoid (hard or fixed), cartilage (and flexible), (like the thread), fibrous and elements of the bone marrow (soft, stock go spongy bone in the middle). Therefore, there are a variety of primary bone cancer that affects each component of bone. These cancers include:
• Osteosarcoma: osteosarcoma is a cancer whose origin of osteoid tissue. This type of cancer occurs most commonly on the knee and the upper hand to win. Osteosarcoma most commonly in children and young adults to find.
• Chondrosarcoma: Chondrosarcoma is a cancer that originated from the cartilage. This type of cancer occurs most often in the upper part of the pelvis, legs, and shoulders. Chondrosarcoma are most commonly found in older adults.
• Ewing Sarcoma family of tumors (ESFTs): this cancer usually occur in the bones, but can also occur in the soft tissues, such as muscles, fat, connective tissue, blood vessels, or other supporting tissue. It is not clear that where cancer was first formed, but it is believed that cancer was based on nerve tissue inside the bone. This type of cancer occurs most often along the spine, pelvis, legs and hands. ESFTs is most common in children and young adults.
• Pleomorphic sarcoma of the bone (malignant fibrous Histiocytoma): this type of cancer is a type of soft tissue tumor, but about 5% of cases appear in the bones. Usually occurs in adults and can be found in every part of the body.
• Fibrosarcoma: Fibrosarcoma is a type of bone cancer, which is rare. This usually occurs in adults and its location on the back of the knee.
Causes of bone cancer
The exact cause of bone cancer are unknown, but the condition will be accepted that are caused by changes or mutations in the DNA structure of the control of cell growth, so that it continues to uncontrollably grow. Accumulation of these cells then form a tumor that can invade nearby bone structure spread or even on other parts of the body.
Here are some factors increase the risk of someone supposedly from bone cancer affected:
• High exposure to radiation from a treatment of affected, such as radiotherapy ever experienced.
• Never have a history of a type of eye cancer retinoblastoma if little known.
• Suffer from Li-Fraumeni syndrome, a rare genetic disorder.
• Paget’s disease, a condition, a weakening of the bones can cause.
• Hernia of Umbilitikus disease since birth.
Bone cancer treatment
Treatment of bone cancer depending on the type, size, location, stage (stage) cancers, as well as age and condition of the protection for victims. There are many different treatment options for bone cancer available are among other dissection (surgery), chemotherapy, radiation therapy (radiotherapy) or cryosurgery.
• Chemotherapy is a treatment with anti-drugs of cancer to kill cancer cells. Usually the anti-cancer drugs combination patients with bone cancer. This time but not more chemotherapy to treat Chondrosarcoma.
• Radiation therapy, radiation therapy with x-rays (x-rays) called, to kill cancer cells. This treatment is used in combination with surgery. Radiation therapy is often used to treat Chondrosarcoma and ESFT, as well as for patients to refuse the operation.
• is the treatment with cryosurgery with liquid nitrogen, which is defined to freeze and kill cancer cells.